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Autophagy activation promotes bevacizumab resistance in glioblastoma by suppressing Akt/mTOR signaling pathway

Glioblastomas are the most common primary and malignant brain tumors. The standard therapy includes surgery and radiotherapy plus chemotherapy, with additional bevacizumab to block the angiogenesis in tumors. However, the ever-growing tolerance of glioblastomas to chemotherapeutic drugs impairs the...

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Bibliografiske detaljer
Udgivet i:Oncol Lett
Main Authors: Huang, He, Song, Jian, Liu, Zheng, Pan, Li, Xu, Guozheng
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774481/
https://ncbi.nlm.nih.gov/pubmed/29434840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7446
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