Oncogenic Ras is downregulated by ARHI and induces autophagy by Ras/AKT/mTOR pathway in glioblastoma

BACKGROUND: Glioblastoma is a disease with high heterogeneity that has long been difficult for doctors to identify and treat. ARHI is a remarkable tumor suppressor gene in human ovarian cancer and many other cancers. We found over-expression of ARHI can also inhibit cancer cell proliferation, decrea...

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Gepubliceerd in:BMC Cancer
Hoofdauteurs: Zhong, Chen, Shu, Mengting, Ye, Junyi, Wang, Xiaoxiong, Chen, Xin, Liu, Zhendong, Zhao, Wenyang, Zhao, Boxian, Zheng, Zhixing, Yin, Zhiqin, Gao, Ming, Zhao, Haiqi, Wang, Kaikai, Zhao, Shiguang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515631/
https://ncbi.nlm.nih.gov/pubmed/31088402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5643-z
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