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Renal IL-18 Production Is Macrophage Independent During Obstructive Injury
BACKGROUND: Interleukin 18 (IL-18) is a pro-inflammatory cytokine that mediates fibrotic renal injury during obstruction. Macrophages are a well-known source of IL-18; however, renal tubular epithelial cells are also a potential source of this cytokine. We hypothesized that IL-18 is predominantly a...
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| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3470595/ https://ncbi.nlm.nih.gov/pubmed/23077611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047417 |
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