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IL-18 STIMULATES A POSITIVE FEEDBACK LOOP DURING RENAL OBSTRUCTION VIA THE IL-18 RECEPTOR
BACKGROUND: IL-18 is a pro-inflammatory cytokine that has recently been demonstrated to be an important mediator of obstruction-induced renal tubulointerstitial fibrosis independent of TNF-α and TGF-β1 activity. We hypothesized that IL-18 stimulates a positive feedback loop during obstruction via th...
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| Udgivet i: | J Urol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520633/ https://ncbi.nlm.nih.gov/pubmed/21855933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2011.05.046 |
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