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IL-18 mediates proapoptotic signaling in renal tubular cells through a Fas ligand-dependent mechanism
Renal tubular cell apoptosis is a significant component of obstruction-induced renal injury, and it results in a progressive loss in renal parenchymal mass during renal obstruction. Although IL-18 is an important mediator of inflammatory renal disease and renal fibrosis, its role in obstruction-indu...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129877/ https://ncbi.nlm.nih.gov/pubmed/21511702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00339.2010 |
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