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TSC2 modulates cell adhesion and migration via integrin-α1β1

Recent evidence suggests that the rare and progressive lung disease lymphangioleiomyomatosis (LAM) is metastatic in nature. Dysfunction of the tumor suppressor genes tuberous sclerosis complex (TSC), in particular mutational inactivation of TSC2, enhances both cell proliferation and migration. Altho...

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Détails bibliographiques
Auteurs principaux: Moir, Lyn M., Black, Judith L., Krymskaya, Vera P.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469633/
https://ncbi.nlm.nih.gov/pubmed/22923640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00414.2011
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