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TSC2 modulates cell adhesion and migration via integrin-α1β1

Recent evidence suggests that the rare and progressive lung disease lymphangioleiomyomatosis (LAM) is metastatic in nature. Dysfunction of the tumor suppressor genes tuberous sclerosis complex (TSC), in particular mutational inactivation of TSC2, enhances both cell proliferation and migration. Altho...

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Detalles Bibliográficos
Main Authors: Moir, Lyn M., Black, Judith L., Krymskaya, Vera P.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469633/
https://ncbi.nlm.nih.gov/pubmed/22923640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00414.2011
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