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TSC2 modulates cell adhesion and migration via integrin-α1β1

Recent evidence suggests that the rare and progressive lung disease lymphangioleiomyomatosis (LAM) is metastatic in nature. Dysfunction of the tumor suppressor genes tuberous sclerosis complex (TSC), in particular mutational inactivation of TSC2, enhances both cell proliferation and migration. Altho...

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Detalhes bibliográficos
Main Authors: Moir, Lyn M., Black, Judith L., Krymskaya, Vera P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469633/
https://ncbi.nlm.nih.gov/pubmed/22923640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00414.2011
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