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TSC2 modulates cell adhesion and migration via integrin-α1β1
Recent evidence suggests that the rare and progressive lung disease lymphangioleiomyomatosis (LAM) is metastatic in nature. Dysfunction of the tumor suppressor genes tuberous sclerosis complex (TSC), in particular mutational inactivation of TSC2, enhances both cell proliferation and migration. Altho...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3469633/ https://ncbi.nlm.nih.gov/pubmed/22923640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00414.2011 |
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