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The Critical Cytoplasmic Regions of the αL/β2 Integrin in Rap1-induced Adhesion and Migration
Rap1 is a potent inside-out signal that increases LFA-1 adhesive activity. In this study, we have defined the cytoplasmic region of the αL and β2 integrin that are required for Rap1-stimulated adhesion and subsequent migration on ICAM-1. Human LFA-1 bearing truncated and point-mutated αL and β2 cyto...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Cell Biology
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC194904/ https://ncbi.nlm.nih.gov/pubmed/12808052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-09-0615 |
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