The Critical Cytoplasmic Regions of the αL/β2 Integrin in Rap1-induced Adhesion and Migration

Rap1 is a potent inside-out signal that increases LFA-1 adhesive activity. In this study, we have defined the cytoplasmic region of the αL and β2 integrin that are required for Rap1-stimulated adhesion and subsequent migration on ICAM-1. Human LFA-1 bearing truncated and point-mutated αL and β2 cyto...

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Publié dans:	Mol Biol Cell
Auteurs principaux:	Tohyama, Yumi, Katagiri, Koko, Pardi, Ruggero, Lu, Chafen, Springer, Timothy A., Kinashi, Tatsuo
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Cell Biology 2003
Sujets:	Articles
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC194904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12808052/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-09-0615
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