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Adenovirus-mediated expression of mutated forkhead human transcription like-1 suppresses tumor growth in a mouse melanoma xenograft model

Melanoma is generally resistant to chemotherapy, which may be related to defects in death receptor signaling and to defects in induction of apoptosis. Forkhead family transcription factors induce the expression of death receptor ligands such as Fas ligand (Fas-L) resulting in apoptosis. We therefore...

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Detalhes bibliográficos
Main Authors: Gomez-Gutierrez, Jorge G., Egger, Michael E., Hao, Hongying, Zhou, Heshan Sam, McMasters, Kelly M.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469477/
https://ncbi.nlm.nih.gov/pubmed/22892845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21349
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