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Adenovirus-Mediated FKHRL1/TM Sensitizes Melanoma Cells to Apoptosis Induced by Temozolomide

Melanoma exhibits variable resistance to the alkylating agent temozolomide (TMZ). We evaluated the potential of adenovirus expressing forkhead human transcription factor like 1 triple mutant (Ad-FKHRL1/TM) to sensitize melanoma cells to TMZ. Four melanoma cell lines were treated with Ad-FKHRL1/TM an...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther Clin Dev
Main Authors: Egger, Michael E., McNally, Lacey R., Nitz, Jonathan, McMasters, Kelly M., Gomez-Gutierrez, Jorge G.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227438/
https://ncbi.nlm.nih.gov/pubmed/25238278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2014.022
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