Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity

The two DNA strands of the nuclear genome are replicated asymmetrically using three DNA polymerases, α, δ, and ε. Current evidence suggests that DNA polymerase ε (Pol ε) is the primary leading strand replicase, whereas Pols α and δ primarily perform lagging strand replication. The fact that these po...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Lujan, Scott A., Williams, Jessica S., Pursell, Zachary F., Abdulovic-Cui, Amy A., Clark, Alan B., Nick McElhinny, Stephanie A., Kunkel, Thomas A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469411/
https://ncbi.nlm.nih.gov/pubmed/23071460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003016
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