Exonucleolytic proofreading of leading and lagging strand DNA replication errors.

We have asked whether exonucleolytic proofreading occurs during simian virus 40 origin-dependent, bidirectional DNA replication in extracts of human HeLa cells. In addition, we have compared the fidelity of leading and lagging strand DNA synthesis. In a fidelity assay that scores single-base substit...

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Dettagli Bibliografici
Autori principali: Roberts, J D, Thomas, D C, Kunkel, T A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC51468/
https://ncbi.nlm.nih.gov/pubmed/1901658
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