cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation

Cellular inhibitor of apoptosis proteins (cIAPs) have emerged as important anti-cell death mediators, particularly in cancer. Although they are known to be expressed in immune tissue, their specific immune function remains unclear. We observed that degradation of cIAPs with SMAC mimetic (SM) results...

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שמור ב:
מידע ביבליוגרפי
Main Authors: McComb, S, Cheung, H H, Korneluk, R G, Wang, S, Krishnan, L, Sad, S
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2012
נושאים:
Original Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469059/
https://ncbi.nlm.nih.gov/pubmed/22576661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.59
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