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cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation
Cellular inhibitor of apoptosis proteins (cIAPs) have emerged as important anti-cell death mediators, particularly in cancer. Although they are known to be expressed in immune tissue, their specific immune function remains unclear. We observed that degradation of cIAPs with SMAC mimetic (SM) results...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3469059/ https://ncbi.nlm.nih.gov/pubmed/22576661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.59 |
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