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Foxp3 Expression is Required for the Induction of Therapeutic Tissue Tolerance()

CD4(+)Foxp3(+) Treg are essential for immune homeostasis and maintenance of self-tolerance. They are produced in the thymus and also generated de novo in the periphery in a TGFβ dependent manner. Foxp3(+) Treg are also required to achieve tolerance to transplanted tissues when induced by co receptor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Regateiro, Frederico S., Chen, Ye, Kendal, Adrian R., Hilbrands, Robert, Adams, Elizabeth, Cobbold, Stephen P., Ma, Jianbo, Andersen, Kristian G., Betz, Alexander G., Zhang, Mindy, Madhiwalla, Shruti, Roberts, Bruce, Waldmann, Herman, Nolan, Kathleen F., Howie, Duncan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467196/
https://ncbi.nlm.nih.gov/pubmed/22988034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200449
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