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Foxp3 Expression is Required for the Induction of Therapeutic Tissue Tolerance()
CD4(+)Foxp3(+) Treg are essential for immune homeostasis and maintenance of self-tolerance. They are produced in the thymus and also generated de novo in the periphery in a TGFβ dependent manner. Foxp3(+) Treg are also required to achieve tolerance to transplanted tissues when induced by co receptor...
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| Auteurs principaux: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3467196/ https://ncbi.nlm.nih.gov/pubmed/22988034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200449 |
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