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Foxp3 Expression is Required for the Induction of Therapeutic Tissue Tolerance()

CD4(+)Foxp3(+) Treg are essential for immune homeostasis and maintenance of self-tolerance. They are produced in the thymus and also generated de novo in the periphery in a TGFβ dependent manner. Foxp3(+) Treg are also required to achieve tolerance to transplanted tissues when induced by co receptor...

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Autors principals: Regateiro, Frederico S., Chen, Ye, Kendal, Adrian R., Hilbrands, Robert, Adams, Elizabeth, Cobbold, Stephen P., Ma, Jianbo, Andersen, Kristian G., Betz, Alexander G., Zhang, Mindy, Madhiwalla, Shruti, Roberts, Bruce, Waldmann, Herman, Nolan, Kathleen F., Howie, Duncan
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467196/
https://ncbi.nlm.nih.gov/pubmed/22988034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200449
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