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Foxp3 drives oxidative phosphorylation and protection from lipotoxicity
Tregs can adopt a catabolic metabolic program with increased capacity for fatty acid oxidation–fueled oxidative phosphorylation (OXPHOS). It is unclear why this form of metabolism is favored in Tregs and, more specifically, whether this program represents an adaptation to the environment and develop...
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Publicado no: | JCI Insight |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5291728/ https://ncbi.nlm.nih.gov/pubmed/28194435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89160 |
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