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A Novel Role for Triglyceride Metabolism in Foxp3 Expression

Lipid metabolism plays a key role in many cellular processes. We show here that regulatory T cells have enhanced lipid storage within subcellular lipid droplets (LD). They also express elevated amounts of both isoforms of diacylglycerol acyl transferase (DGAT1 & 2), enzymes required for the term...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Howie, Duncan, Ten Bokum, Annemieke, Cobbold, Stephen Paul, Yu, Zhanru, Kessler, Benedikt M., Waldmann, Herman
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701200/
https://ncbi.nlm.nih.gov/pubmed/31456800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01860
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