Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia

Acute leukemias are characterized by deregulation of transcriptional networks that control the lineage specificity of gene expression. The aberrant overexpression of the Spi-1/PU.1 transcription factor leads to erythroleukemia. To determine how Spi-1 mechanistically influences the transcriptional pr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Ridinger-Saison, Maya, Boeva, Valentina, Rimmelé, Pauline, Kulakovskiy, Ivan, Gallais, Isabelle, Levavasseur, Benjamin, Paccard, Caroline, Legoix-Né, Patricia, Morlé, François, Nicolas, Alain, Hupé, Philippe, Barillot, Emmanuel, Moreau-Gachelin, Françoise, Guillouf, Christel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Gene Regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467057/
https://ncbi.nlm.nih.gov/pubmed/22790984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks659
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge