Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia

Acute leukemias are characterized by deregulation of transcriptional networks that control the lineage specificity of gene expression. The aberrant overexpression of the Spi-1/PU.1 transcription factor leads to erythroleukemia. To determine how Spi-1 mechanistically influences the transcriptional pr...

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Autors principals: Ridinger-Saison, Maya, Boeva, Valentina, Rimmelé, Pauline, Kulakovskiy, Ivan, Gallais, Isabelle, Levavasseur, Benjamin, Paccard, Caroline, Legoix-Né, Patricia, Morlé, François, Nicolas, Alain, Hupé, Philippe, Barillot, Emmanuel, Moreau-Gachelin, Françoise, Guillouf, Christel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Gene Regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467057/
https://ncbi.nlm.nih.gov/pubmed/22790984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks659
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