Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation

Graft-versus-host disease (GVHD) remains the most common cause of nonrelapse-related morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Although T-cell depletion and intensive immunosuppression are effective in the control of GVHD, they are often associated...

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Main Authors: Brennan, Todd V., Lin, Liwen, Huang, Xiaopei, Cardona, Diana M., Li, Zhiguo, Dredge, Keith, Chao, Nelson J., Yang, Yiping
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2012
主題:
Transplantation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466971/
https://ncbi.nlm.nih.gov/pubmed/22760779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-368720
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