Flagellin, a TLR5 agonist, reduces GvHD in allogeneic HSCT recipients while enhancing anti-viral immunity

Graft-versus-host disease (GvHD) is a major cause of morbidity and mortality in patients treated with allogeneic hematopoietic stem cell transplantation (HSCT). Post-transplant immunosuppressive drugs incompletely control GvHD and increase susceptibility to opportunistic infections. In this study we...

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Main Authors: Hossain, Mohammad S., Jaye, David L., Pollack, Brian P., Farris, Alton B., Tselanyane, Malefa L., David, Ebenezer, Roback, John D., Gewirtz, Andrew T., Waller, Edmund K.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265143/
https://ncbi.nlm.nih.gov/pubmed/22013117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101334
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