BAFF promotes heightened BCR responsiveness and manifestations of chronic GVHD after allogeneic stem cell transplantation

Patients with chronic graft-versus-host disease (cGVHD) have increased B cell–activating factor (BAFF) levels, but whether BAFF promotes disease after allogeneic bone marrow transplantation (allo-BMT) remains unknown. In a major histocompatibility complex–mismatched model with cGVHD-like manifestati...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Jia, Wei, Poe, Jonathan C., Su, Hsuan, Anand, Sarah, Matsushima, Glenn K., Rathmell, Jeffrey C., Maillard, Ivan, Radojcic, Vedran, Imai, Kazuhiro, Reyes, Nancy J., Cardona, Diana M., Li, Zhiguo, Suthers, Amy N., Curry-Chisolm, Itaevia M., DiCioccio, Rachel A., Saban, Daniel R., Chen, Benny J., Chao, Nelson J., Sarantopoulos, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109011/
https://ncbi.nlm.nih.gov/pubmed/33534893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020008040
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