The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

Fibroblast growth factor-21 (FGF21) is a hormone secreted by the liver during fasting that elicits diverse aspects of the adaptive starvation response. Among its effects, FGF21 induces hepatic fatty acid oxidation and ketogenesis, increases insulin sensitivity, blocks somatic growth and causes bone...

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Dades bibliogràfiques
Autors principals: Zhang, Yuan, Xie, Yang, Berglund, Eric D, Coate, Katie Colbert, He, Tian Teng, Katafuchi, Takeshi, Xiao, Guanghua, Potthoff, Matthew J, Wei, Wei, Wan, Yihong, Yu, Ruth T, Evans, Ronald M, Kliewer, Steven A, Mangelsdorf, David J
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2012
Matèries:
Genes and Chromosomes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466591/
https://ncbi.nlm.nih.gov/pubmed/23066506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00065
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