The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

Fibroblast growth factor-21 (FGF21) is a hormone secreted by the liver during fasting that elicits diverse aspects of the adaptive starvation response. Among its effects, FGF21 induces hepatic fatty acid oxidation and ketogenesis, increases insulin sensitivity, blocks somatic growth and causes bone...

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Bibliografski detalji
Glavni autori: Zhang, Yuan, Xie, Yang, Berglund, Eric D, Coate, Katie Colbert, He, Tian Teng, Katafuchi, Takeshi, Xiao, Guanghua, Potthoff, Matthew J, Wei, Wei, Wan, Yihong, Yu, Ruth T, Evans, Ronald M, Kliewer, Steven A, Mangelsdorf, David J
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2012
Teme:
Genes and Chromosomes
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466591/
https://ncbi.nlm.nih.gov/pubmed/23066506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00065
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