Fibroblast growth factor 21: from pharmacology to physiology(1)(2)(3)(4)

Fibroblast growth factor 21 (FGF21) is an atypical member of the FGF family that functions as an endocrine hormone. Pharmacologic studies show that FGF21 has broad metabolic actions in obese rodents and primates that include enhancing insulin sensitivity, decreasing triglyceride concentrations, and...

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Autori principali: Kliewer, Steven A, Mangelsdorf, David J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Nutrition 2010
Soggetti:
Supplement: Therapeutic Advances for Insulin Resistance and Diabetes: Novel Pathways and the Development of Selective PPARγ Modulators from Bench to Bedside
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793111/
https://ncbi.nlm.nih.gov/pubmed/19906798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.2009.28449B
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