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βKlotho Is Required for Fibroblast Growth Factor 21 Effects On Growth and Metabolism
Fibroblast growth factor 21 (FGF21) is a fasting-induced hepatokine that has potent pharmacologic effects in mice, which include improving insulin sensitivity and blunting growth. The single-transmembrane protein, βKlotho, functions as a co-receptor for FGF21 in vitro. To determine if βKlotho is req...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3447537/ https://ncbi.nlm.nih.gov/pubmed/22958921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.08.002 |
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