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βKlotho is required for metabolic activity of fibroblast growth factor 21
Fibroblast growth factor 21 (FGF21) is a liver-derived endocrine factor that stimulates glucose uptake in adipocytes. Here, we show that FGF21 activity depends on βKlotho, a single-pass transmembrane protein whose expression is induced during differentiation from preadipocytes to adipocytes. βKlotho...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855074/ https://ncbi.nlm.nih.gov/pubmed/17452648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701600104 |
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