βKlotho is required for metabolic activity of fibroblast growth factor 21

Fibroblast growth factor 21 (FGF21) is a liver-derived endocrine factor that stimulates glucose uptake in adipocytes. Here, we show that FGF21 activity depends on βKlotho, a single-pass transmembrane protein whose expression is induced during differentiation from preadipocytes to adipocytes. βKlotho...

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Détails bibliographiques
Auteurs principaux: Ogawa, Yasushi, Kurosu, Hiroshi, Yamamoto, Masaya, Nandi, Animesh, Rosenblatt, Kevin P., Goetz, Regina, Eliseenkova, Anna V., Mohammadi, Moosa, Kuro-o, Makoto
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855074/
https://ncbi.nlm.nih.gov/pubmed/17452648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701600104
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