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Regulation of Oxidative Stress by the Anti-aging Hormone Klotho

klotho is an aging suppressor gene and extends life span when overexpressed in mice. Klotho protein was recently demonstrated to function as a hormone that inhibits insulin/insulin-like growth factor-1 (IGF-1) signaling. Here we show that Klotho protein increases resistance to oxidative stress at th...

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Bibliografiska uppgifter
Huvudupphovsmän: Yamamoto, Masaya, Clark, Jeremy D., Pastor, Johanne V., Gurnani, Prem, Nandi, Animesh, Kurosu, Hiroshi, Miyoshi, Masayoshi, Ogawa, Yasushi, Castrillon, Diego H., Rosenblatt, Kevin P., Kuro-o, Makoto
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515369/
https://ncbi.nlm.nih.gov/pubmed/16186101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M509039200
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