Klotho Coreceptors Inhibit Signaling by Paracrine Fibroblast Growth Factor 8 Subfamily Ligands

It has been recently established that Klotho coreceptors associate with fibroblast growth factor (FGF) receptor tyrosine kinases (FGFRs) to enable signaling by endocrine-acting FGFs. However, the molecular interactions leading to FGF-FGFR-Klotho ternary complex formation remain incompletely understo...

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Auteurs principaux: Goetz, Regina, Ohnishi, Mutsuko, Ding, Xunshan, Kurosu, Hiroshi, Wang, Lei, Akiyoshi, Junko, Ma, Jinghong, Gai, Weiming, Sidis, Yisrael, Pitteloud, Nelly, Kuro-o, Makoto, Razzaque, Mohammed S., Mohammadi, Moosa
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347405/
https://ncbi.nlm.nih.gov/pubmed/22451487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06603-11
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