Conversion of a Paracrine Fibroblast Growth Factor into an Endocrine Fibroblast Growth Factor

FGFs 19, 21, and 23 are hormones that regulate in a Klotho co-receptor-dependent fashion major metabolic processes such as glucose and lipid metabolism (FGF21) and phosphate and vitamin D homeostasis (FGF23). The role of heparan sulfate glycosaminoglycan in the formation of the cell surface signalin...

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Detalhes bibliográficos
Main Authors: Goetz, Regina, Ohnishi, Mutsuko, Kir, Serkan, Kurosu, Hiroshi, Wang, Lei, Pastor, Johanne, Ma, Jinghong, Gai, Weiming, Kuro-o, Makoto, Razzaque, Mohammed S., Mohammadi, Moosa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436551/
https://ncbi.nlm.nih.gov/pubmed/22733815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.342980
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