In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis

A major breakthrough in systemic phosphate homeostasis regulation was achieved by the demonstration of strikingly similar physical, morphological, and biochemical phenotypes of fibroblast growth factor 23 (Fgf23) and klotho ablated mice, which led to identification of klotho as an Fgf23 signaling co...

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Autori principali: Nakatani, Teruyo, Sarraj, Bara, Ohnishi, Mutsuko, Densmore, Michael J., Taguchi, Takashi, Goetz, Regina, Mohammadi, Moosa, Lanske, Beate, Razzaque, M. Shawkat
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Federation of American Societies for Experimental Biology 2009
Soggetti:
Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630784/
https://ncbi.nlm.nih.gov/pubmed/18835926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-114397
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