Does Fgf23-klotho activity influence vascular and soft tissue calcification through regulating phosphate homeostasis?

Recent studies describe a novel role of fibroblast growth factor 23 (Fgf23)-klotho activity in the systemic regulation of calcium and phosphate homeostasis. Both Fgf23 and klotho ablated mice develop extensive vascular and soft tissue calcification. Inability to clear the required amount of phosphat...

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Hlavní autoři: Memon, Fahad, El-Abbadi, Mohga, Nakatani, Teruyo, Taguchi, Takashi, Lanske, Beate, Razzaque, M. Shawkat
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771539/
https://ncbi.nlm.nih.gov/pubmed/18528324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2008.218
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