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Sorafenib, a multikinase inhibitor, is effective in vitro against non-Hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin

Non-Hodgkin lymphoma (NHL) represents a heterogenous group of neoplasias originating from lymphoid cells. Increased angiogenesis and expression of Vascular Endothelial Growth Factor (VEGF) and its receptors (VEGFR) have been found to be associated with NHL disease progression. Increase in VEGF and o...

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Autors principals: Ramakrishnan, Vijay, Timm, Michael, Haug, Jessica L., Kimlinger, Teresa K., Halling, Timothy, Wellik, Linda E., Witzig, Thomas E., Rajkumar, S. Vincent, Adjei, Alex A., Kumar, Shaji
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465673/
https://ncbi.nlm.nih.gov/pubmed/22190165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.22263
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