Sorafenib, a multikinase inhibitor, is effective in vitro against non-Hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin

Non-Hodgkin lymphoma (NHL) represents a heterogenous group of neoplasias originating from lymphoid cells. Increased angiogenesis and expression of Vascular Endothelial Growth Factor (VEGF) and its receptors (VEGFR) have been found to be associated with NHL disease progression. Increase in VEGF and o...

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Main Authors: Ramakrishnan, Vijay, Timm, Michael, Haug, Jessica L., Kimlinger, Teresa K., Halling, Timothy, Wellik, Linda E., Witzig, Thomas E., Rajkumar, S. Vincent, Adjei, Alex A., Kumar, Shaji
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465673/
https://ncbi.nlm.nih.gov/pubmed/22190165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.22263
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