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Selection of antibodies that regulate phenotype from intracellular combinatorial antibody libraries
A method is presented that uses combinatorial antibody libraries to endow cells with new binding energy landscapes for the purpose of regulating their phenotypes. Antibodies that are expressed in cells infected with a lentiviral combinatorial antibody library are selected directly for function rathe...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465454/ https://ncbi.nlm.nih.gov/pubmed/23019357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214275109 |
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