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Selection of antibodies that regulate phenotype from intracellular combinatorial antibody libraries

A method is presented that uses combinatorial antibody libraries to endow cells with new binding energy landscapes for the purpose of regulating their phenotypes. Antibodies that are expressed in cells infected with a lentiviral combinatorial antibody library are selected directly for function rathe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhang, Hongkai, Wilson, Ian A., Lerner, Richard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465454/
https://ncbi.nlm.nih.gov/pubmed/23019357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214275109
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