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Autocrine signaling based selection of combinatorial antibodies that transdifferentiate human stem cells

We report here the generation of antibody agonists from intracellular combinatorial libraries that transdifferentiate human stem cells. Antibodies that are agonists for the granulocyte colony stimulating factor receptor were selected from intracellular libraries on the basis of their ability to acti...

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Bibliografske podrobnosti
Main Authors: Xie, Jia, Zhang, Hongkai, Yea, Kyungmoo, Lerner, Richard A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657831/
https://ncbi.nlm.nih.gov/pubmed/23613575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306263110
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