In Vivo Selection of Transplanted Hepatocytes by Pharmacological Inhibition of Fumarylacetoacetate Hydrolase in Wild-type Mice

Genetic fumarylacetoacetate hydrolase (Fah) deficiency is unique in that healthy gene-corrected hepatocytes have a strong growth advantage and can repopulate the diseased liver. Unfortunately, similar positive selection of gene-corrected cells is absent in most inborn errors of liver metabolism and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Paulk, Nicole K, Wursthorn, Karsten, Haft, Annelise, Pelz, Carl, Clarke, Gregory, Newell, Amy H, Olson, Susan B, Harding, Cary O, Finegold, Milton J, Bateman, Raymond L, Witte, John F, McClard, Ronald, Grompe, Markus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2012
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464641/
https://ncbi.nlm.nih.gov/pubmed/22871666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.154
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