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A universal system to select gene-modified hepatocytes in vivo
Many genetic and acquired liver disorders are amenable to gene and/or cell therapy. However, the efficiencies of cell engraftment and stable genetic modification are low and often sub-therapeutic. In particular, targeted gene modifications from homologous recombination are rare events. These obstacl...
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| Publicado no: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5242329/ https://ncbi.nlm.nih.gov/pubmed/27280686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad8166 |
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