CD8 Lineage-specific Regulation of Interleukin-7 Receptor Expression by the Transcriptional Repressor Gfi1

Interleukin-7 receptor α (IL-7Rα) is essential for T cell survival and differentiation. Glucocorticoids are potent enhancers of IL-7Rα expression with diverse roles in T cell biology. Here we identify the transcriptional repressor, growth factor independent-1 (Gfi1), as a novel intermediary in gluco...

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Dades bibliogràfiques
Autors principals: Ligons, Davinna L., Tuncer, Ceren, Linowes, Brett A., Akcay, Izzet Mehmet, Kurtulus, Sema, Deniz, Emre, Atasever Arslan, Belkis, Cevik, Safak Isil, Keller, Hilary R., Luckey, Megan A., Feigenbaum, Lionel, Möröy, Tarik, Ersahin, Tulin, Atalay, Rengul, Erman, Batu, Park, Jung-Hyun
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464544/
https://ncbi.nlm.nih.gov/pubmed/22865857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378687
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