CD8 Lineage-specific Regulation of Interleukin-7 Receptor Expression by the Transcriptional Repressor Gfi1

Interleukin-7 receptor α (IL-7Rα) is essential for T cell survival and differentiation. Glucocorticoids are potent enhancers of IL-7Rα expression with diverse roles in T cell biology. Here we identify the transcriptional repressor, growth factor independent-1 (Gfi1), as a novel intermediary in gluco...

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書誌詳細
主要な著者: Ligons, Davinna L., Tuncer, Ceren, Linowes, Brett A., Akcay, Izzet Mehmet, Kurtulus, Sema, Deniz, Emre, Atasever Arslan, Belkis, Cevik, Safak Isil, Keller, Hilary R., Luckey, Megan A., Feigenbaum, Lionel, Möröy, Tarik, Ersahin, Tulin, Atalay, Rengul, Erman, Batu, Park, Jung-Hyun
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2012
主題:
Immunology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464544/
https://ncbi.nlm.nih.gov/pubmed/22865857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378687
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