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PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function
Insults to cellular health cause p53 protein accumulation, and loss of p53 function leads to tumorigenesis. Thus, p53 has to be tightly controlled. Here we report that the BTB/POZ domain transcription factor PATZ1 (MAZR), previously known for its transcriptional suppressor functions in T lymphocytes...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4405645/ https://ncbi.nlm.nih.gov/pubmed/25755280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01475-14 |
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