PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function

Insults to cellular health cause p53 protein accumulation, and loss of p53 function leads to tumorigenesis. Thus, p53 has to be tightly controlled. Here we report that the BTB/POZ domain transcription factor PATZ1 (MAZR), previously known for its transcriptional suppressor functions in T lymphocytes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Keskin, Nazli, Deniz, Emre, Eryilmaz, Jitka, Un, Manolya, Batur, Tugce, Ersahin, Tulin, Cetin Atalay, Rengul, Sakaguchi, Shinya, Ellmeier, Wilfried, Erman, Batu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2015
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405645/
https://ncbi.nlm.nih.gov/pubmed/25755280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01475-14
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