PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function

Insults to cellular health cause p53 protein accumulation, and loss of p53 function leads to tumorigenesis. Thus, p53 has to be tightly controlled. Here we report that the BTB/POZ domain transcription factor PATZ1 (MAZR), previously known for its transcriptional suppressor functions in T lymphocytes...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Keskin, Nazli, Deniz, Emre, Eryilmaz, Jitka, Un, Manolya, Batur, Tugce, Ersahin, Tulin, Cetin Atalay, Rengul, Sakaguchi, Shinya, Ellmeier, Wilfried, Erman, Batu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405645/
https://ncbi.nlm.nih.gov/pubmed/25755280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01475-14
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