CD8 Lineage-specific Regulation of Interleukin-7 Receptor Expression by the Transcriptional Repressor Gfi1

Interleukin-7 receptor α (IL-7Rα) is essential for T cell survival and differentiation. Glucocorticoids are potent enhancers of IL-7Rα expression with diverse roles in T cell biology. Here we identify the transcriptional repressor, growth factor independent-1 (Gfi1), as a novel intermediary in gluco...

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Detaylı Bibliyografya
Asıl Yazarlar: Ligons, Davinna L., Tuncer, Ceren, Linowes, Brett A., Akcay, Izzet Mehmet, Kurtulus, Sema, Deniz, Emre, Atasever Arslan, Belkis, Cevik, Safak Isil, Keller, Hilary R., Luckey, Megan A., Feigenbaum, Lionel, Möröy, Tarik, Ersahin, Tulin, Atalay, Rengul, Erman, Batu, Park, Jung-Hyun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464544/
https://ncbi.nlm.nih.gov/pubmed/22865857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378687
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