Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis

Targeting bacterial essential genes using antisense phosphorodiamidate morpholino oligomers (PMOs) represents an important strategy in the development of novel antibacterial therapeutics. PMOs are neutral DNA analogues that inhibit gene expression in a sequence-specific manner. In this study, severa...

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Bibliografiske detaljer
Main Authors: Panchal, Rekha G., Geller, Bruce L., Mellbye, Brett, Lane, Douglas, Iversen, Patrick L., Bavari, Sina
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2012
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464405/
https://ncbi.nlm.nih.gov/pubmed/22978365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0362
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