Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis

Targeting bacterial essential genes using antisense phosphorodiamidate morpholino oligomers (PMOs) represents an important strategy in the development of novel antibacterial therapeutics. PMOs are neutral DNA analogues that inhibit gene expression in a sequence-specific manner. In this study, severa...

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Bibliografski detalji
Glavni autori: Panchal, Rekha G., Geller, Bruce L., Mellbye, Brett, Lane, Douglas, Iversen, Patrick L., Bavari, Sina
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2012
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464405/
https://ncbi.nlm.nih.gov/pubmed/22978365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0362
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