Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis

Targeting bacterial essential genes using antisense phosphorodiamidate morpholino oligomers (PMOs) represents an important strategy in the development of novel antibacterial therapeutics. PMOs are neutral DNA analogues that inhibit gene expression in a sequence-specific manner. In this study, severa...

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Bibliographische Detailangaben
Hauptverfasser: Panchal, Rekha G., Geller, Bruce L., Mellbye, Brett, Lane, Douglas, Iversen, Patrick L., Bavari, Sina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2012
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464405/
https://ncbi.nlm.nih.gov/pubmed/22978365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0362
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