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Variations in Amino Acid Composition of Antisense Peptide-Phosphorodiamidate Morpholino Oligomer Affect Potency against Escherichia coli In Vitro and In Vivo

The potency of antisense peptide-phosphorodiamidate morpholino oligomers (PPMOs) was improved by varying the peptide composition. An antisense phosphorodiamidate morpholino oligomer (PMO) complementary to the mRNA of the essential gene acpP (which encodes the acyl carrier protein required for lipid...

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書誌詳細
主要な著者: Mellbye, Brett L., Puckett, Susan E., Tilley, Luke D., Iversen, Patrick L., Geller, Bruce L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630659/
https://ncbi.nlm.nih.gov/pubmed/19015356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00917-08
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