Bacterial Resistance to Antisense Peptide Phosphorodiamidate Morpholino Oligomers

Peptide phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA mimics that bind cRNA and inhibit bacterial gene expression. The PPMO (RFF)(3)RXB-AcpP (where R is arginine, F, phenylalanine, X is 6-aminohexanoic acid, B is β-alanine, and AcpP is acyl carrier protein) is complementary to 11...

Full description

Saved in:
Bibliographic Details
Main Authors: Puckett, Susan E., Reese, Kaleb A., Mitev, Georgi M., Mullen, Valerie, Johnson, Rudd C., Pomraning, Kyle R., Mellbye, Brett L., Tilley, Lucas D., Iversen, Patrick L., Freitag, Michael, Geller, Bruce L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497173/
https://ncbi.nlm.nih.gov/pubmed/22985881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00850-12
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items